Researchers have identified a genetic mutation that they believe may be a cause of lupus through a recent study that they believe could lead to therapies which could target the mutation in people. Using a mouse model researchers focused on a specific gene to find whether or not it was linked to lupus. The gene POL B focuses on DNA repair; decreased POL B expression leads to weakened DNA repair which they have linked to lupus. Senior author Joann Sweasy says “This finding implicates abnormal DNA repair as one of the causes of lupus in people.” This study may possibly lead to a better understanding of how this abnormal DNA repair is linked to lupus and possibly new ways to treat the disease. This is a great discovery to kick off the new year with and hopefully much more will come of it.